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Interferon regulatory factors 1 and 4 in T cell mediated immune modulation
The transcription factor interferon regulatory factor (IRF) 1 is essential for T helper cell 1 differentiation. Hereby, the respective Irf1 knockout mouse displays a severe immune defect and has an Th2 directed immune status per se. This effect is measurable by increased production of interleukin-4,...
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| Formato: | Dissertation |
| Idioma: | inglés |
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Philipps-Universität Marburg
2011
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| Schlagworte: | |
| Acceso en liña: | Texto completo PDF |
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