Interferon regulatory factors 1 and 4 in T cell mediated immune modulation

The transcription factor interferon regulatory factor (IRF) 1 is essential for T helper cell 1 differentiation. Hereby, the respective Irf1 knockout mouse displays a severe immune defect and has an Th2 directed immune status per se. This effect is measurable by increased production of interleukin-4,...

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1. Verfasser: Mahiny, Azita Josefine
Beteiligte: Lohoff, Michael (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2011
Hygiene u. Med. Mikrobiologie mit Medizinaluntersuchungsamt
Ausgabe:http://dx.doi.org/10.17192/z2011.0561
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