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Pituitary adenylate cyclase-activating polypeptide mediates differential signaling through PAC1 receptor splice variants and activates non-canonical cAMP dependent gene induction in the nervous system - Implications for homeostatic stress-responding
Pituitary adenylate cyclase-activating polypeptide (PACAP)-mediated activation of its G protein-coupled receptor PAC1 results in activation of the two G proteins Gs and Gq to alter second messenger generation and gene transcription in the nervous system, important for homeostatic responses to stress...
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| 格式: | Dissertation |
| 语言: | 英语 |
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Philipps-Universität Marburg
2011
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| 在线阅读: | PDF-Volltext |
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