Pituitary adenylate cyclase-activating polypeptide mediates differential signaling through PAC1 receptor splice variants and activates non-canonical cAMP dependent gene induction in the nervous system - Implications for homeostatic stress-responding

Pituitary adenylate cyclase-activating polypeptide mediates differential signaling through PAC1 receptor splice variants and activates non-canonical cAMP dependent gene induction in the nervous system - Implications for homeostatic stress-responding

Pituitary adenylate cyclase-activating polypeptide (PACAP)-mediated activation of its G protein-coupled receptor PAC1 results in activation of the two G proteins Gs and Gq to alter second messenger generation and gene transcription in the nervous system, important for homeostatic responses to stress...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Holighaus, Yvonne
مؤلفون آخرون: Weihe, Eberhard (Prof. Dr.) (مرشد الأطروحة)
التنسيق: Dissertation
اللغة:الإنجليزية
منشور في: Philipps-Universität Marburg 2011
الموضوعات:
nervous system
Nervensystem
G protein-coupled receptors
signal transduction
Neuropeptide
G-Protein gekoppelte Rezeptoren
neuropharmacology
Neuropharmakologie
stress
PACAP
neuropeptides
Signaltransduktion
Naturwissenschaften
Genexpression
Stress
gene expression
Natural sciences & mathematics
الوصول للمادة أونلاين:PDF النص الكامل
الوسوم: إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

مواد مشابهة