Analyse biologischer Effekte eines Fibroblasten-Wachstumsfaktor-bindenden Proteins (FGF-BP) in Tumoren über verschiedene Knockdown-Strategien

Fibroblasten Wachstumsfaktoren (FGFs) spielen eine bedeutende Rolle bei der Zellproliferation und -differenzierung. Bei neoplastischem Wachstum fungieren FGFs als potente Mitogene. Einige der tumorrelevanten FGFs binden jedoch mit hoher Affinität an eine oder mehrere Komponenten der extrazellulären...

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Main Author: Schulze, Daniel
Contributors: Kissel, Thomas (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2011
Pharmazeutische Technologie und Biopharmazie
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