Analysis of a capsid-modified and conditionally replicating, oncolytic adenoviral vector as a novel treatment for human glioblastoma multiforme.

Analysis of a capsid-modified and conditionally replicating, oncolytic adenoviral vector as a novel treatment for human glioblastoma multiforme.

Glioblastoma multiforme (GBM) is the most aggressive brain tumor, and patients rarely survive for more than 2 years. Gene therapy may offer new treatment options and improve the prognosis for patients with GBM. Adenovirus-mediated gene therapy strategies for brain tumors have been limited by ineffic...

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Détails bibliographiques
Auteur principal: Wohlfahrt, Martin E.
Autres auteurs: Lingelbach, Klaus (Prof.) (Directeur de thèse)
Format: Dissertation
Langue:anglais
Publié: Philipps-Universität Marburg 2010
Sujets:
Onkolyse
Glioblastom
Oncolysis
Adenovirus 5
Naturwissenschaften
Glioblastoma multiforme, TRAIL
TRAIL
Adenovirus
Natural sciences & mathematics
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