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Synthesis and Analytics of Rigidified Peptide Architectures: Neuropeptide Y Dipeptide Scan, Ring-Chain-Equilibria of Iminopeptides, Thiazole Amino Acids for Thiopeptide Antibiotics
The architectures (three-dimensional shapes) of peptides determine their respective biological functions. Therefore, the correct alignment of functionalities in a structure by constraining the flexibility is a key process in evolution as well as in medicinal chemistry in order to increase binding af...
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| Формат: | Dissertation |
| Язык: | английский |
| Опубликовано: |
Philipps-Universität Marburg
2010
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| Online-ссылка: | PDF-полный текст |
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