Untersuchungen zur Lipoinitiation während der nichtribosomalen Synthese von Daptomycin und Surfactin

Die zyklischen Lipopeptid-Antibiotika stellen eine Klasse strukturell verwandter und bioaktiver Oligopeptide dar, welche durch multimodular aufgebaute Enzymkomplexe, den nichtribosomalen Peptidsynthetasen (NRPS) assembliert werden. Essenziell für die antibiotische Aktivität ist die mit dem Peptidrüc...

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Main Author: Wittmann, Melanie
Contributors: Marahiel, Mohamed A. (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2010
Chemie
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