Toxicological Evaluation of Poly(ethylene imine) -based non-viral vector systems for pulmonary siRNA application

Toxicological Evaluation of Poly(ethylene imine) -based non-viral vector systems for pulmonary siRNA application

In this thesis, toxicity of PEI-based non-viral vector systems for siRNA application into the lungs was comprehensively described and analyzed in vitro as well as in vivo. Chapter 1 introduced in basic information about the lung anatomy and physiology and general considerations for pulmonary appli...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Beyerle, Andrea
Otros Autores: Kissel, Thomas (Prof.) (Orientador)
Formato: Dissertation
Lenguaje:inglés
Publicado: Philipps-Universität Marburg 2010
Materias:
inflammation
Polyethylenimin (PEI)
pulmonary application
RNS-Interferenz
siRNA
Toxikologische Bewertung
Naturwissenschaften
Cytotoxicity
Wasserlösliche Polymere
Oxidativer Stress
Entzündung
In vivo
Lunge
Cytotoxizität
In vitro
Poly(ethylene imine)
oxidative stress
Natural sciences & mathematics
Acceso en línea:Texto Completo PDF
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares