Regulation of proto-oncogenic Pim-1 kinase and miR-17-92 microRNAcluster in the human leukemia cell line K562

Regulation of proto-oncogenic Pim-1 kinase and miR-17-92 microRNAcluster in the human leukemia cell line K562

In this thesis the regulation of the oncogenic kinase Pim-1 and the microRNA cluster miR-17-92 has been investigated using the leukemia cell line K562 as a model system. Pim-1 and miR-17-92 have been reported to be highly expressed in the context of leukemia cells as well as in other cancer cell lin...

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Bibliografski detalji
Glavni autor: Prinz, Robert
Daljnji autori: Hartmann, Roland Karl (Prof. Dr.) (Savjetnik disertacije)
Format: Dissertation
Jezik:engleski
Izdano: Philipps-Universität Marburg 2009
Teme:
Cancer
Pim-1
K562
Leukämie
Naturwissenschaften
miR-17-92
Small RNA
miR-33
Krebs
Antisense-RNS
B-Zell-Leukämie
Gen-Targeting
Natural sciences & mathematics
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