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The well-tempered Thrombin - A systematic crystallographic and calorimetric study on the thermodynamics of serine-protease inhibition
The presented study contributes to the fundamental understanding of molecular recognition of small molecules by a macromolecular host protein. The biophysical properties of a large set of systematically varied thrombin inhibitors were anatomized in detail. In particular the combination of structural...
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| 其他作者: | |
| 格式: | Dissertation |
| 语言: | 英语 |
| 出版: |
Philipps-Universität Marburg
2009
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| 主题: | |
| 在线阅读: | PDF-Volltext |
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PDF-Volltext| 索引号: |
urn:nbn:de:hebis:04-z2009-06981 |
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| Publikationsdatum: |
2009-11-24 |
| Datum der Annahme: |
2009-08-28 |
| Downloads: |
59 (2024), 148 (2023), 204 (2022), 240 (2021), 330 (2020), 289 (2019), 131 (2018) |
| Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
| 访问URL: |
https://archiv.ub.uni-marburg.de/diss/z2009/0698 https://doi.org/10.17192/z2009.0698 |