The well-tempered Thrombin - A systematic crystallographic and calorimetric study on the thermodynamics of serine-protease inhibition

The well-tempered Thrombin - A systematic crystallographic and calorimetric study on the thermodynamics of serine-protease inhibition

The presented study contributes to the fundamental understanding of molecular recognition of small molecules by a macromolecular host protein. The biophysical properties of a large set of systematically varied thrombin inhibitors were anatomized in detail. In particular the combination of structural...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Kaituhi matua: Baum, Bernhard
Ētahi atu kaituhi: Klebe, Gerhard (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Hōputu: Dissertation
Reo:Ingarihi
I whakaputaina: Philipps-Universität Marburg 2009
Ngā marau:
Thermodynamik
Wirkstoffdesign
Kristallographie
Mikrokalorimetrie
Structure based drug-design
Thrombin
Arzneimitteldesign
Naturwissenschaften
Natural sciences & mathematics
Urunga tuihono:Kuputuhi katoa PDF
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ipurangi

Kuputuhi katoa PDF

Ngā taipitopito puringa mai i
Tau karanga: urn:nbn:de:hebis:04-z2009-06981
Rā whakaputa: 2009-11-24
Datum der Annahme: 2009-08-28
Downloads: 59 (2024), 148 (2023), 204 (2022), 240 (2021), 330 (2020), 289 (2019), 131 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
Zugangs-URL: https://archiv.ub.uni-marburg.de/diss/z2009/0698
https://doi.org/10.17192/z2009.0698

Ngā tūemi rite