The well-tempered Thrombin - A systematic crystallographic and calorimetric study on the thermodynamics of serine-protease inhibition

The presented study contributes to the fundamental understanding of molecular recognition of small molecules by a macromolecular host protein. The biophysical properties of a large set of systematically varied thrombin inhibitors were anatomized in detail. In particular the combination of structural...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile nagusia: Baum, Bernhard
Beste egile batzuk: Klebe, Gerhard (Prof. Dr.) (Tesi aholkularia)
Formatua: Dissertation
Hizkuntza:ingelesa
Argitaratua: Philipps-Universität Marburg 2009
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Internet

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Aleari buruzko argibideak
Sailkapena: urn:nbn:de:hebis:04-z2009-06981
Argitaratze data: 2009-11-24
Datum der Annahme: 2009-08-28
Downloads: 59 (2024), 148 (2023), 204 (2022), 240 (2021), 330 (2020), 289 (2019), 131 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL sarbidea: https://archiv.ub.uni-marburg.de/diss/z2009/0698
https://doi.org/10.17192/z2009.0698