The well-tempered Thrombin - A systematic crystallographic and calorimetric study on the thermodynamics of serine-protease inhibition
The presented study contributes to the fundamental understanding of molecular recognition of small molecules by a macromolecular host protein. The biophysical properties of a large set of systematically varied thrombin inhibitors were anatomized in detail. In particular the combination of structural...
Wedi'i Gadw mewn:
Prif Awdur: | |
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Awduron Eraill: | |
Fformat: | Dissertation |
Iaith: | Saesneg |
Cyhoeddwyd: |
Philipps-Universität Marburg
2009
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Pynciau: | |
Mynediad Ar-lein: | Testun PDF llawn |
Tagiau: |
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Rhyngrwyd
Testun PDF llawnRhif Galw: |
urn:nbn:de:hebis:04-z2009-06981 |
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Dyddiad Cyhoeddi: |
2009-11-24 |
Datum der Annahme: |
2009-08-28 |
Downloads: |
59 (2024), 148 (2023), 204 (2022), 240 (2021), 330 (2020), 289 (2019), 131 (2018) |
Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
URL mynediad: |
https://archiv.ub.uni-marburg.de/diss/z2009/0698 https://doi.org/10.17192/z2009.0698 |