Investigation of the functions of 53BP1 in DNA demethylation

DNA damage can be caused by various forms of genotoxic stress, including endogenous (reactive oxygen species, abnormal replication intermediates) and exogenous (UV, IR, and reactive chemicals) sources. DNA double-strand break (DSB) is believed to be one of the most serious lesions to cells becaus...

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Bibliographic Details
Main Author: Wang, Linfang
Contributors: Engenhart-Cabillic, R. (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2009
Klinik für Strahlentherapie
Online Access:PDF Full Text
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