Investigation of the Phosphorylation of theC-terminal domains of the cardiac MyosinBinding Protein C by the 5-AMP-activatedProtein Kinase

Investigation of the Phosphorylation of theC-terminal domains of the cardiac MyosinBinding Protein C by the 5-AMP-activatedProtein Kinase

The existence of MyBP-C in striated muscle has been known for over 35 years and about 150 mutations in the gene encoding cMyBP-C have been found to be a common cause of hypertrophic cardiomyopathy. Despite this, the structure and function of MyBP-C remains less well understood than most other sarc...

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Bibliographic Details
Main Author: Renz, Bernhard Willibald
Contributors: Aumüller, Gerhard (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2009
Subjects:
Hypertrophe Kardiomyopathie
Kardiales Myosin Bindungsprotein
Medizin
Phosphorylierung
AMP-aktivierten Proteinkinase
AMPK
Phosphorylation
cMyBP-C
HCM
Medical sciences Medicine
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