Investigation of the Phosphorylation of theC-terminal domains of the cardiac MyosinBinding Protein C by the 5-AMP-activatedProtein Kinase
The existence of MyBP-C in striated muscle has been known for over 35 years and about 150 mutations in the gene encoding cMyBP-C have been found to be a common cause of hypertrophic cardiomyopathy. Despite this, the structure and function of MyBP-C remains less well understood than most other sarc...
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Format: | Dissertation |
Sprache: | Englisch |
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Philipps-Universität Marburg
2009
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