Carbonyl Reductases and Pluripotent HydroxysteroidDehydrogenases of the Short-Chain Dehydrogenase/ReductaseSuperfamily:Structural Aspects of Oligomerization in 3alpha-HydroxysteroidDehydrogenase /Carbonyl Reductase from Comamonas testosteroni:New Approaches for efficient Protein Design

Carbonyl Reductases and Pluripotent HydroxysteroidDehydrogenases of the Short-Chain Dehydrogenase/ReductaseSuperfamily:Structural Aspects of Oligomerization in 3alpha-HydroxysteroidDehydrogenase /Carbonyl Reductase from Comamonas testosteroni:New Approaches for efficient Protein Design

Carbonyl reduction of aldehydes, ketones and quinones to their corresponding hydroxy de-rivatives plays an important role in the phase-I metabolism of many endogenous (biogenic aldehydes, steroids, prostaglandins, reactive lipid peroxidation products) and xenobiotic (pharmacologic drugs, carcinogens...

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Bibliographische Detailangaben
1. Verfasser: Hoffmann-Geim, Frank
Beteiligte: Buckel, Wolfgang (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2009
Schlagworte:
Simulation
Modellierung
Biowissenschaften, Biologie
Carbonyl-Reductase
Röntgenstruktur
Drug Design
Hydroxysteroid-Dehydrogenasen
SDR
Molekulardynamik
3alpha HSD/CR
Molecular dynamic
Hydroxysteroiddehydrogenase
Life sciences
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Signatur: urn:nbn:de:hebis:04-z2009-05639
Publikationsdatum: 2009-10-08
Datum der Annahme: 2009-07-17
Downloads: 46 (2024), 91 (2023), 45 (2022), 41 (2021), 35 (2020), 66 (2019), 33 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
Zugangs-URL: https://archiv.ub.uni-marburg.de/diss/z2009/0563
https://doi.org/10.17192/z2009.0563

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