Unusual Building Blocks and Domain Organization of Non-Ribosomal Peptide Synthetases

Unusual Building Blocks and Domain Organization of Non-Ribosomal Peptide Synthetases

The diverse class of non-ribosomal peptides consists of manifold pharmacologically important natural products. They are clinically used in antibiotic, antiviral and antitumor therapy, furthermore some are known immunosuppresants. The biological activity is based on their structural diversity, as the...

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Dettagli Bibliografici
Autore principale: Strieker, Matthias
Altri autori: Marahiel, Mohamed A. (Prof. Dr.) (Relatore della tesi)
Natura: Dissertation
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2009
Soggetti:
Naturstoff
Tailoring
Hydroxylierung
Beta-hydroxyaminosäuren
Modifikation <Biochemie>
Antibiotics
Chemie
Antibiotikum
Nonproteinogenic amino acids
Aminosäuren
Modification
NRPS
Chemistry & allied sciences
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