Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Muconyl-CoA, 2-hydroxyadipoyl-CoA, oxalocrotonyl-CoA and butynedioyl- CoA were synthesised and characterised as substrates of the (R)-2- hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum. The specificity of the enzyme for these substrates were determined and the reaction products identi...

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Detalhes bibliográficos
Autor principal: Parthasarathy, Anutthaman
Outros Autores: Buckel, Wolfgang (Prof. Dr.) (Orientador)
Formato: Dissertation
Idioma:inglês
Publicado em: Philipps-Universität Marburg 2009
Assuntos:
[4Fe-4S] Cluster
Hydroxyglutaryl-CoA-Dehydratase <2->
Clostridium propionicum
2-hydroxyglutaryl-CoA, lactyl-CoA
2-Hydroxyglutarat-Dehydrogenase
Biowissenschaften, Biologie
Coenzym A
Clostridium symbiosum
Acidaminococcus fermentans
Dehydratase
Lactyl-CoA, Dehydration
[4Fe-4S] cluster
Life sciences
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