Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Muconyl-CoA, 2-hydroxyadipoyl-CoA, oxalocrotonyl-CoA and butynedioyl- CoA were synthesised and characterised as substrates of the (R)-2- hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum. The specificity of the enzyme for these substrates were determined and the reaction products identi...

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Bibliographic Details
Main Author: Parthasarathy, Anutthaman
Contributors: Buckel, Wolfgang (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2009
Subjects:
Hydroxyglutaryl-CoA-Dehydratase <2->
Clostridium propionicum
[4Fe-4S] Cluster
Biowissenschaften, Biologie
Coenzym A
Lactyl-CoA, Dehydration
Acidaminococcus fermentans
[4Fe-4S] cluster
Clostridium symbiosum
2-Hydroxyglutarat-Dehydrogenase
2-hydroxyglutaryl-CoA, lactyl-CoA
Dehydratase
Life sciences
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Call Number: urn:nbn:de:hebis:04-z2009-01552
Publication Date: 2009-07-03
Date of Acceptance: 2009-06-05
Downloads: 39 (2024), 66 (2023), 112 (2022), 100 (2021), 32 (2020), 41 (2019), 15 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2009/0155
https://doi.org/10.17192/z2009.0155

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