Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Muconyl-CoA, 2-hydroxyadipoyl-CoA, oxalocrotonyl-CoA and butynedioyl- CoA were synthesised and characterised as substrates of the (R)-2- hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum. The specificity of the enzyme for these substrates were determined and the reaction products identi...

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Autor principal: Parthasarathy, Anutthaman
Altres autors: Buckel, Wolfgang (Prof. Dr.) (Assessor de tesis)
Format: Dissertation
Idioma:anglès
Publicat: Philipps-Universität Marburg 2009
Matèries:
Hydroxyglutaryl-CoA-Dehydratase <2->
Clostridium propionicum
[4Fe-4S] Cluster
Biowissenschaften, Biologie
Coenzym A
Lactyl-CoA, Dehydration
Acidaminococcus fermentans
[4Fe-4S] cluster
Clostridium symbiosum
2-Hydroxyglutarat-Dehydrogenase
2-hydroxyglutaryl-CoA, lactyl-CoA
Dehydratase
Life sciences
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Signatura: urn:nbn:de:hebis:04-z2009-01552
Data de publicació: 2009-07-03
Datum der Annahme: 2009-06-05
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Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL d'accés: https://archiv.ub.uni-marburg.de/diss/z2009/0155
https://doi.org/10.17192/z2009.0155

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