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The Role of the Mitotic Spindle Checkpoint in Chemotherapy-Induced Apoptosis
The mitotic spindle assembly checkpoint (SCP) is a signal transduction pathway that ensures proper chromosome segregation during mitosis by inhibiting the onset of anaphase until all chromosomes are properly aligned. It requires a group of highly conserved proteins including Mad1, Mad2, Bub1, BubR1,...
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| Format: | Doctoral Thesis |
| Language: | English |
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Philipps-Universität Marburg
2008
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| Online Access: | PDF Full Text |
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