The Role of the Mitotic Spindle Checkpoint in Chemotherapy-Induced Apoptosis

The mitotic spindle assembly checkpoint (SCP) is a signal transduction pathway that ensures proper chromosome segregation during mitosis by inhibiting the onset of anaphase until all chromosomes are properly aligned. It requires a group of highly conserved proteins including Mad1, Mad2, Bub1, BubR1,...

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Bibliografiske detaljer
Hovedforfatter: Vogel, Celia
Andre forfattere: Bastians, Holger (Dr.) (BetreuerIn (Doktorarbeit))
Format: Dissertation
Sprog:engelsk
Udgivet: Philipps-Universität Marburg 2008
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