Structure-based Development of Secondary Amines as Aspartic Protease Inhibitors
As novel promising scaffold for HIV protease inhibition pyrrolidine-derived inhibitors have recently been reported. In this thesis the stepwise improvement of this compound class to potent inhibitors of wildtype as well as selected mutant proteases utilizing rational drug discovery methods is report...
Na minha lista:
Autor principal: | |
---|---|
Outros Autores: | |
Formato: | Dissertation |
Idioma: | inglês |
Publicado em: |
Philipps-Universität Marburg
2008
|
Assuntos: | |
Acesso em linha: | Texto integral em PDF |
Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|
Internet
Texto integral em PDFÁrea/Cota: |
urn:nbn:de:hebis:04-z2009-00750 |
---|---|
Publikationsdatum: |
2009-03-03 |
Datum der Annahme: |
2008-11-21 |
Downloads: |
40 (2024), 59 (2023), 230 (2022), 200 (2021), 159 (2020), 183 (2019), 225 (2018) |
Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
Zugangs-URL: |
https://archiv.ub.uni-marburg.de/diss/z2009/0075 https://doi.org/10.17192/z2009.0075 |