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Structure-based Development of Secondary Amines as Aspartic Protease Inhibitors
As novel promising scaffold for HIV protease inhibition pyrrolidine-derived inhibitors have recently been reported. In this thesis the stepwise improvement of this compound class to potent inhibitors of wildtype as well as selected mutant proteases utilizing rational drug discovery methods is report...
保存先:
| 第一著者: | |
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| その他の著者: | |
| フォーマット: | Dissertation |
| 言語: | 英語 |
| 出版事項: |
Philipps-Universität Marburg
2008
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| 主題: | |
| オンライン･アクセス: | PDFフルテキスト |
| タグ: |
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インターネット
PDFフルテキスト| 請求記号: |
urn:nbn:de:hebis:04-z2009-00750 |
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| 出版日付: |
2009-03-03 |
| Datum der Annahme: |
2008-11-21 |
| Downloads: |
40 (2024), 59 (2023), 230 (2022), 200 (2021), 159 (2020), 183 (2019), 225 (2018) |
| Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
| アクセスURL: |
https://archiv.ub.uni-marburg.de/diss/z2009/0075 https://doi.org/10.17192/z2009.0075 |