Identifizierung von Aurora-A als essentielles Protein im MYCN-amplifizierten Neuroblastom und Relevanz der c-Myc/Miz1-Interaktion für die MYC-induzierte Tumorgenese in vivo

Myc-Onkoproteine (c-Myc, N-Myc und L-Myc) sind in einer Vielzahl humaner maligner Tumore in erhöhten Mengen nachgewiesen worden und in der Lage, in verschiedenen Mausmodellen maligne Tumore zu induzieren. Dabei wurden die onkogenen Funktionen von Myc bisher größtenteils einer transkriptionellen Akti...

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Bibliographic Details
Main Author: Otto, Tobias
Contributors: Renkawitz-Pohl, Renate (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2008
Biologie
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Call Number: urn:nbn:de:hebis:04-z2008-10004
Downloads: 200 (2020), 240 (2019), 134 (2018), 106 (2017), 127 (2016)
Source: Cancer Cell (2009) 15, 1-12
Publication Date: 2009-01-12
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2008/1000
https://doi.org/10.17192/z2008.1000