Die SUMOylierung des Transkriptionsfaktors Sp3 reprimiert die Genexpression durch Rekrutierung Chromatin-modifizierender Enzyme und Ausbildung lokaler heterochromatischer Strukturen

Die posttranslationale Modifikation vieler Transkriptionsfaktoren mit dem Ubiquitin-ähnlichen Protein SUMO (Small Ubiquitin-like Modifier) führt oft zur transkriptionellen Repression. Der molekulare Mechanismus, wie die SUMO-Modifikation die Transkription reprimiert, war noch weitgehend unbekannt. U...

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Bibliographic Details
Main Author: Stielow, Bastian
Contributors: Suske, Guntram (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2008
Molekularbiologie und Tumorforschung
Subjects:
Sp3
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Call Number: http://archiv.ub.uni-marburg.de/diss/z2008/0985
https://doi.org/10.17192/z2008.0985
urn:nbn:de:hebis:04-z2008-09857
Downloads: 63 (2019), 55 (2018), 66 (2017), 57 (2016)
Publication Date: 2009-01-12
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author.