Non-Viral Gene Delivery Systems: Studies on HER2-Targeted PEG-PEI Copolymers and Modified Chitosans

Non-Viral Gene Delivery Systems: Studies on HER2-Targeted PEG-PEI Copolymers and Modified Chitosans

In this thesis new non-viral gene delivery systems were synthesized and characterized. In the first part different questions concerning in vitro and in vivo gene delivery using HER2-targeted Polyethylenglycol (PEG)-modified Polyethylenimine (PEI) polyplexes were addressed. The second part deals with...

Cur síos iomlán

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Sonraí bibleagrafaíochta
Príomhchruthaitheoir: Germershaus, Oliver
Rannpháirtithe: Kissel, Thomas (Prof. Dr.) (Comhairleoir tráchtais)
Formáid: Dissertation
Teanga:Béarla
Foilsithe / Cruthaithe: Philipps-Universität Marburg 2008
Ábhair:
Gentransfer
Gene therapy
Polyethylenimin
Modifizierte Polymere
Modified Polymers
Naturwissenschaften
Tiermodell
Pharmacokinetics
Polyethyleniminderivate
Pharmakokinetik
Polyethylenimine
Biodistribution
Plasmid
Zellkultur
Natural sciences & mathematics
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