Ganganalyse bei Parkinson-Patienten mit Tiefer Hirnstimulation unter Verwendung des Pedar-XSystems Inaugural-Dissertation

In former studies it was found that patients suffering from Parkinson disease show a special appearance of gait: With increasing motorical affection the patient leans more and more forward. The aim of this study was an evaluation of whether it is possible to use the pedar-x-system (an insole-pressure-measurement-system) for a gait analysis on patients suffering from Parkinson disease who have been treated by deep brain stimulation. The basic aim was to find out whether turning on and off the stimulation results in different pressure measurements and whether these differences correlate with a typical appearance of the gait of a Parkinson patient. Second aim was to determine whether the motorically more affected side of the patient showed corresponding measurements. 10 patients had to walk a distance of ten meters, first with stimulation switched on and then after having switching off the stimulation, as soon as the symptoms were the same as before surgery. For data-analysis each insole was devided into 10 different anatomical areas of the foot. At first for each anatomical foot area the mean pressure distribution of all patients was calculated with stimulation on and off. Statistically significant results for the lateral and medial heel and significant tendencies for the central and lateral forefood were found, that strongly indicate a bending forward of the body. Afterwards for each single patient the pressure distribution was calculated with stimulation switched on and off, regarding the motorically more and less affected side of the body. 7 out of 10 patients showed results corresponding to the clinical signs, however here no statistically significant results were achieved.