Effects of the antimicrobial peptide LL-37 in combination with hyperthermic preconditioning on the outcome of septic rats

Effects of the antimicrobial peptide LL-37 in combination with hyperthermic preconditioning on the outcome of septic rats

Summary Background: We studied the effects of LL-37 prophylaxis or therapy on the outcome after intra-abdominal sepsis and tested whether additional preconditioning with fever-range hyperthermia augments host immune response and improves survival. Methods: A rat model of peritoneal contamination...

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Bibliographic Details
Main Author: Gurschi, Eugeniu
Contributors: Bauhofer, A. (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2008
Subjects:
Bakterielle Infektion
MIP-2
LD50
Präkonditionierung
Hyperthermie
LL-37
Mikrobielle Kontamination
Standardisierte humane Stuhlsuspension
Medizin
Sepsis
Antimikrobieller Wirkstoff
HSP70
CMRT
Hyperthermischer Präkonditionierung
LPS
Peritoneal Contamination and Infection
Medical sciences Medicine
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