Die Röntgenstrukturen der Glutamatdehydrogenase von Plasmodium falciparum und der Liponamiddehydrogenase von Trypanosoma cruzi. Zielmoleküle für das strukturbasierte Design neuer antiparasitärer Wirkstoffe

In der vorliegenden Arbeit wurden die Kristallstrukturen der Glutamatdehydrogenase des Malariaerregers Plasmodium falciparum und der Liponamiddehydrogenase von Trypanosoma cruzi, dem Erreger der Chagas-Krankheit, aufgeklärt. Beide Enzyme sind validierte bzw. mögliche Zielmoleküle für das rationale D...

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Bibliographic Details
Main Author: Werner, Christof
Contributors: Klebe, Gerhard (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2008
Pharmazeutische Chemie
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Call Number: urn:nbn:de:hebis:04-z2008-01584
Downloads: 90 (2020), 102 (2019), 78 (2018), 36 (2017), 27 (2016)
Publication Date: 2008-06-24
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2008/0158
https://doi.org/10.17192/z2008.0158