Effekte von Adipositas und Geschlecht auf die Eigenschaften der oberen Atemwege und auf kompensatorische respiratorische Antworten bei oberen Atemwegsobstruktionen

Die obstruktive Schlafapnoe, welche mit rezidivierenden Atemstillständen im Schlaf aufgrund eines Kollaps der oberen Atemwege einhergeht, weist zahlreiche Risikofaktoren auf. Die wichtigsten bekannten Faktoren sind männliches Geschlecht und Übergewicht. Diese Studie untersucht, wie Übergewicht und G...

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Detaylı Bibliyografya
Yazar: Canisius, Sebastian
Diğer Yazarlar: Schneider, Hartmut (Dr.) (Tez danışmanı)
Materyal Türü: Dissertation
Dil:Almanca
Baskı/Yayın Bilgisi: Philipps-Universität Marburg 2007
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Obstructive sleep apnea is characteritzed by repetitive cessations of breathing during the night. These cessations are caused by collapsing upper airways. Although there exist several known risk factors for obstructive sleep apnea (OSAS) among which are obesity and male gender, the pathophysiologic effects of these factors are still unknown. This study investigates the influences of obesity on strucutral properties of the upper as well as on the compensatory reactions to upper airway obstructions. Secondly, influences of gender on these two parameters are investigated. In summary, obesity mainly effects the structural properties of the upper airways, while male gender obviously alters the compensatory reactions to upper airway obstructions, making them ineffective.