The surfactin biosynthetic complex of Bacillus subtilis: COM domain-mediated biocombinatorial synthesis, and single step purification of native multi-modular NRPSs and multi-enzyme complexes

The surfactin biosynthetic complex of Bacillus subtilis: COM domain-mediated biocombinatorial synthesis, and single step purification of native multi-modular NRPSs and multi-enzyme complexes

Most biosynthetic templates for the assembly of peptide natural products are composed of two or more nonribosomal peptide synthetases (NRPSs). For example, the surfactin biosynthetic complex consists of three NRPSs (SrfA-A, SrfA-B, and SrfA-C), which are encoded by the polycistronic srfA operon with...

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Bibliografiska uppgifter
Huvudupphovsman: Chiocchini, Claudia
Övriga upphovsmän: Buckel, Wolfgang (Prof.) (BetreuerIn (Doktorarbeit))
Materialtyp: Dissertation
Språk:engelska
Publicerad: Philipps-Universität Marburg 2006
Ämnen:
Multienzyme complexes
Multienzymkomplex
Biochemistry, molecular biology
COM domains
Protein-protein communication
Biowissenschaften, Biologie
NRPS
COM Domäne
Protein-Protein-Wechselwirkung
Life sciences
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Signum: urn:nbn:de:hebis:04-z2006-08381
Utgivningstid: 2006-12-21
Datum der Annahme: 2006-06-29
Downloads: 89 (2024), 48 (2023), 49 (2022), 89 (2021), 65 (2020), 71 (2019), 38 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
Länk till materialet: https://archiv.ub.uni-marburg.de/diss/z2006/0838
https://doi.org/10.17192/z2006.0838

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