The surfactin biosynthetic complex of Bacillus subtilis: COM domain-mediated biocombinatorial synthesis, and single step purification of native multi-modular NRPSs and multi-enzyme complexes

The surfactin biosynthetic complex of Bacillus subtilis: COM domain-mediated biocombinatorial synthesis, and single step purification of native multi-modular NRPSs and multi-enzyme complexes

Most biosynthetic templates for the assembly of peptide natural products are composed of two or more nonribosomal peptide synthetases (NRPSs). For example, the surfactin biosynthetic complex consists of three NRPSs (SrfA-A, SrfA-B, and SrfA-C), which are encoded by the polycistronic srfA operon with...

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Autor principal: Chiocchini, Claudia
Otros Autores: Buckel, Wolfgang (Prof.) (Orientador)
Formato: Dissertation
Lenguaje:inglés
Publicado: Philipps-Universität Marburg 2006
Materias:
Multienzyme complexes
Multienzymkomplex
Biochemistry, molecular biology
COM domains
Protein-protein communication
Biowissenschaften, Biologie
NRPS
COM Domäne
Protein-Protein-Wechselwirkung
Life sciences
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Número de Clasificación: urn:nbn:de:hebis:04-z2006-08381
Fecha de Publicación: 2006-12-21
Datum der Annahme: 2006-06-29
Downloads: 85 (2024), 48 (2023), 49 (2022), 89 (2021), 65 (2020), 71 (2019), 38 (2018)
Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL de Acceso: https://archiv.ub.uni-marburg.de/diss/z2006/0838
https://doi.org/10.17192/z2006.0838

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