The surfactin biosynthetic complex of Bacillus subtilis: COM domain-mediated biocombinatorial synthesis, and single step purification of native multi-modular NRPSs and multi-enzyme complexes

Most biosynthetic templates for the assembly of peptide natural products are composed of two or more nonribosomal peptide synthetases (NRPSs). For example, the surfactin biosynthetic complex consists of three NRPSs (SrfA-A, SrfA-B, and SrfA-C), which are encoded by the polycistronic srfA operon with...

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Manylion Llyfryddiaeth
Prif Awdur: Chiocchini, Claudia
Awduron Eraill: Buckel, Wolfgang (Prof.) (Cynghorydd traethodau ymchwil)
Fformat: Dissertation
Iaith:Saesneg
Cyhoeddwyd: Philipps-Universität Marburg 2006
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Rhif Galw: urn:nbn:de:hebis:04-z2006-08381
Dyddiad Cyhoeddi: 2006-12-21
Datum der Annahme: 2006-06-29
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Lizenz: https://rightsstatements.org/vocab/InC-NC/1.0/
URL mynediad: https://archiv.ub.uni-marburg.de/diss/z2006/0838
https://doi.org/10.17192/z2006.0838