Insulin nanocomplexes formed by self-assembly from amine-modified poly(vinyl alcohol)-graft-poly(L-Lactide) for non-invasive mucosal delivery: Preparation, characterization and in vivo investigations
In this work biodegradable DEAPA-PVAL-g-PLLA nanocomplexes were investigated as a colloidal peptide carrier system for non-invasive transmucosal insulin delivery. Chapter 1 describes the basic fundamentals of insulin therapy, current status, problems and future trends. The pathogenesis of diabetes m...
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Format: | Dissertation |
Sprache: | Englisch |
Veröffentlicht: |
Philipps-Universität Marburg
2005
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Schlagworte: | |
Online Zugang: | PDF-Volltext |
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PDF-VolltextSignatur: |
urn:nbn:de:hebis:04-z2006-00763 |
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Publikationsdatum: |
2006-03-03 |
Datum der Annahme: |
2005-12-05 |
Quelle: |
Bioconjugate Chemistry 15(4) 841-849 , 2005. Pharmaceutical Research 22(11) 1879-86, 2005. |
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https://rightsstatements.org/vocab/InC-NC/1.0/ |
Zugangs-URL: |
https://archiv.ub.uni-marburg.de/diss/z2006/0076 https://doi.org/10.17192/z2006.0076 |