Ein Beitrag zur Ätiologie peptischer Ulcera im Zeitalter der Eradikationstherapie von Helicobacter pylori

Ungefähr 5-10% der Bevölkerung entwickeln im Laufe des Lebens ein peptisches Ulcus. Als wichtigste Risikofaktoren der peptischen Ulcuskrankheit gelten das Bakterium Helicobacter pylori und die Einnahme von nicht-steroidalen Antirheumatika. Frühe Studien der 80er und 90er Jahre zeigten, dass mehr a...

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Bibliographic Details
Main Author: Tiedge, Stefanie
Contributors: Eissele, Rolf (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2006
Innere Medizin
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Table of Contents: About 5 to 10 per cent of the population suffer from peptic ulcer disease during their lives. The main risk factors are the bacterium helicobacter pylori and medication with nonsteroidal antiinflammatory drugs (nsaids). In the 80`s and 90`s more than 90 per cent of duodenal ulcers and about 70 per cent of gastric ulcers were associated with helicobacter pylori. For this reason patients were regularly treated by an eradication of the bacterium. In the last years an increase of patients with peptic ulcers not associated with helicobacter pylori nor nsaids was reported. Our aim was to investigate the situation of peptic ulcer disease in a german university hospital: how many peptic ulcer are associated with helicobacter pylori and/ or nsaids and are there other risk factors?