Chitosan copolymers for intranasal delivery of insulin: synthesis, characterization and biological properties

Recently, chitosan has been extensively investigated as a promising carrier in the field of drug delivery. To overcome its poor solubility at physiological pH and the cytotoxicity of trimethyl chitosan, PEGylated trimethyl chitosan copolymers were synthesized and characterized systemically for the f...

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Bibliographic Details
Main Author: Mao, Shirui
Contributors: Kissel, Thomas (Prof.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2004
Pharmazeutische Technologie und Biopharmazie
Online Access:PDF Full Text
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