Prä- und postoperative neuropsychiatrische Befunde bei Patienten mit primärem Hyperparathyreoidismus

Fragestellung vorliegender Untersuchung ist die Häufigkeit und die Veränderung neuropsychiatrischer Symptome bei Patienten mit primärem Hyperparathyreoidismus vor und nach Parathyreoidektomie. Es wurden die folgenden zwei Hypothesen überprüft und bestätigt. Erstens: Patienten mit pHP...

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Autore principale: Hanke, Tobias
Altri autori: Schreiber, Wolfgang (Prof. Dr. med. ) (Relatore della tesi)
Natura: Dissertation
Lingua:tedesco
Pubblicazione: Philipps-Universität Marburg 2003
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In this study 39 patients with pHPT and 22 patients with benign thyroid disease underwent psychiatric ratings before and after parathyroid surgery. The psychiatric symptoms were evaluated using the Symptom-Checklist-90-Revised (SCL-90-R), Becks Depression Inventary (BDI), Hamilton Depression Scale (HAMD), Montgomery Asberg Depression Scale (MADRS) and three measurements of cognition. The hyperparathyreoid group had preoperatively significantly higher (p<0.05) levels of psychiatric symptoms. The factors for anxiety, depression, and cognitive symptoms were the most pronounced in the pHPT patients and were also decrease after surgery.