Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potential

Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potential

Mitochondrial dysfunction is strongly implicated in the etiology of idiopathic and genetic Parkinson’s disease (PD). However, strategies aimed at ameliorating mitochondrial dysfunction, including antioxidants, antidiabetic drugs, and iron chelators, have failed in disease-modification clinical tri...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Henrich, Martin T., Oertel, Wolfgang H., Surmeier, D. James, Geibl, Fanni F.
Fformat: Erthygl
Iaith:Saesneg
Cyhoeddwyd: Philipps-Universität Marburg 2024
Pynciau:
MPTP
Neuroprotective therapies
Medizin
Mitochondria
Mitochondrial dysfunction
Parkinson’s disease
Electron transport chain, Antioxidants
Synuclein
Medical sciences Medicine
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