Ehf and Fezf2 regulate late medullary thymic epithelial cell and thymic tuft cell development

Ehf and Fezf2 regulate late medullary thymic epithelial cell and thymic tuft cell development

Thymic epithelial cells are indispensable for T cell maturation and selection and the induction of central immune tolerance. The self-peptide repertoire expressed by medullary thymic epithelial cells is in part regulated by the transcriptional regulator Aire (Autoimmune regulator) and the transcr...

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Autori principali: Lammers, Sören, Barrera, Victor, Brennecke, Philip, Miller, Corey, Yoon, Joon, Balolong, Jared, Anderson, Mark S., Ho Sui, Shannan, Steinmetz, Lars M., Andrian, Ulrich H. von, Rattay, Kristin
Natura: Articolo
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2024
Soggetti:
central tolerance
Medizin
Ehf
medullary thymic epithelial cell
thymus
Fezf2
Tuft cells
Medical sciences Medicine
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