A novel mass cytometry protocol optimized for immunophenotyping of low-frequency antigen-specific T cells

A novel mass cytometry protocol optimized for immunophenotyping of low-frequency antigen-specific T cells

Understanding antigen-specific T-cell responses, for example, following virus infections or allergen exposure, is of high relevance for the development of vaccines and therapeutics. We aimed on optimizing immunophenotyping of T cells after antigen stimulation by improving staining procedures for...

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Autori principali: Balz, Kathrin, Grange, Magali, Pegel, Uta, Karamya, Zain A., Mello, Marielle, Zhou, Xiaoying, Berger, Thilo, Bloch, Konstantin, Dunham, Diane, Chinthrajah, Sharon, Nadeau, Kari, Luche, Hervé, Skevaki, Chrysanthi
Natura: Articolo
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2024
Soggetti:
sample barcoding
CyTOF
Medizin
T-cell activation
T-cell stimulation assay
method
Medical sciences Medicine
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