High expression of insulinoma-associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrinecarcinomas from conventional adenocarcinomas with diffuseexpression of synaptophysin

High expression of insulinoma-associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrinecarcinomas from conventional adenocarcinomas with diffuseexpression of synaptophysin

Complementary to synaptophysin and chromogranin A, insulinoma-associated protein 1 (INSM1) has emerged as a sensitive marker for the diagnosis of neuroendocrine neoplasms. Since there are no comparative data regarding INSM1 expression in conventional colorectal adenocarcinomas (CRCs) and colorectal...

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Autoren: Litmeyer, Anne-Sophie, Konukiewitz, Björn, Kasajima, Atsuko, Foersch, Sebastian, Schicktanz, Felix, Schmitt, Maxime, Kellers, Franziska, Grass, Albert, Jank, Paul, Lehman, Bettina, Gress, Thomas M., Rinke, Anja, Bartsch, Detlef K., Denkert, Carsten, Weichert, Wilko, Klöppel, Günter, Jesinghaus, Moritz
Format: Artikel
Sprache:Englisch
Veröffentlicht: Philipps-Universität Marburg 2023
Schlagworte:
neuroendocrine carcinoma
colorectal carcinoma
conventional adenocarcinoma
INSM1
Medizin
synaptophysin
Medical sciences Medicine
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