Trans-ancestry polygenic models for the prediction of LDL blood levels: an analysis of the United Kingdom Biobank and Taiwan Biobank

Trans-ancestry polygenic models for the prediction of LDL blood levels: an analysis of the United Kingdom Biobank and Taiwan Biobank

Polygenic risk score (PRS) predictions often show bias toward the population of available genome-wide association studies (GWASs), which is typically of European ancestry. This study aimed to assess the performance differences of ancestry-specific PRS and test the implementation of multi-ancestry PR...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Hassanin, Emadeldin, Lee, Ko-Han, Hsieh, Tzung-Chien, Aldisi, Rana, Lee, Yi-Lun, Bobbili, Dheeraj, Krawitz, Peter, May, Patrick, Chen, Chien-Yu, Maj, Carlo
स्वरूप: लेख
भाषा:अंग्रेज़ी
प्रकाशित: Philipps-Universität Marburg 2023
विषय:
East Asia
LDL cholesterol
United Kingdom Biobank
Taiwan Biobank
polygenic risk score
Medizin
Medical sciences Medicine
ऑनलाइन पहुंच:पीडीएफ पूर्ण पाठ
टैग: टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
टिप्पणी देने वाले पहले व्यक्ति बनें!
आपको पहले लॉग इन होना चाहिए

समान संसाधन