Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy

Márquez-Tirado, Bárbara; Gutiérrez-Tenorio, Josué; Tortajada, Agustín; Lucientes Continente, Laura; Caravaca-Fontán, Fernando; Malik, Talat H.; Roldán Montero, Raquel; Elías, Sandra; Saiz Gonzalez, Ana; Fernández-Juarez, Gema; Sánchez-Corral, Pilar; Pickering, Matthew C; Praga, Manuel; Rodríguez de Córdoba, Santiago; Goicoechea de Jorge, Elena

Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy

Background: C3 glomerulopathy (C3G) is a heterogeneous group of chronic renal diseases characterized predominantly by glomerular C3 deposition and complement dysregulation. Mutations in factor H–related (FHR) proteins resulting in duplicated dimerization domains are prototypical of C3G, although the...

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Autoren:	Márquez-Tirado, Bárbara, Gutiérrez-Tenorio, Josué, Tortajada, Agustín, Lucientes Continente, Laura, Caravaca-Fontán, Fernando, Malik, Talat H., Roldán Montero, Raquel, Elías, Sandra, Saiz Gonzalez, Ana, Fernández-Juarez, Gema, Sánchez-Corral, Pilar, Pickering, Matthew C, Praga, Manuel, Rodríguez de Córdoba, Santiago, Goicoechea de Jorge, Elena
Format:	Artikel
Sprache:	Englisch
Veröffentlicht:	Philipps-Universität Marburg 2022
Schlagworte:	Medizin Medical sciences Medicine
Online-Zugang:	PDF-Volltext
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Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy

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