Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy

Márquez-Tirado, Bárbara; Gutiérrez-Tenorio, Josué; Tortajada, Agustín; Lucientes Continente, Laura; Caravaca-Fontán, Fernando; Malik, Talat H.; Roldán Montero, Raquel; Elías, Sandra; Saiz Gonzalez, Ana; Fernández-Juarez, Gema; Sánchez-Corral, Pilar; Pickering, Matthew C; Praga, Manuel; Rodríguez de Córdoba, Santiago; Goicoechea de Jorge, Elena

Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy

Background: C3 glomerulopathy (C3G) is a heterogeneous group of chronic renal diseases characterized predominantly by glomerular C3 deposition and complement dysregulation. Mutations in factor H–related (FHR) proteins resulting in duplicated dimerization domains are prototypical of C3G, although the...

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Главные авторы:	Márquez-Tirado, Bárbara, Gutiérrez-Tenorio, Josué, Tortajada, Agustín, Lucientes Continente, Laura, Caravaca-Fontán, Fernando, Malik, Talat H., Roldán Montero, Raquel, Elías, Sandra, Saiz Gonzalez, Ana, Fernández-Juarez, Gema, Sánchez-Corral, Pilar, Pickering, Matthew C, Praga, Manuel, Rodríguez de Córdoba, Santiago, Goicoechea de Jorge, Elena
Формат:	Статья
Язык:	английский
Опубликовано:	Philipps-Universität Marburg 2022
Предметы:	Medizin Medical sciences Medicine
Online-ссылка:	PDF-полный текст
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Factor H–Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy

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