PACAP regulates VPAC1 expression, inflammatory processes and lipid homeostasis in M1- and M2-macrophages

PACAP regulates VPAC1 expression, inflammatory processes and lipid homeostasis in M1- and M2-macrophages

Background: Pituitary adenylate cyclase-activating polypeptide (PACAP) acts as an anti-atherogenic neuropeptide and plays an important role in cytoprotective, as well as inflammatory processes, and cardiovascular regulation. Therefore, the aim of this study is to investigate the regulatory effect...

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Autori principali: Witzel, Roman, Block, Annika, Pollmann, Solvey, Oetzel, Leandra, Fleck, Fenja, Bonaterra, Gabriel A., Kinscherf, Ralf, Schwarz, Anja
Natura: Articolo
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2023
Soggetti:
inflammation
Medizin
macrophages
oxLDL
PACAP
atherosclerosis
VPAC1
Medical sciences Medicine
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