Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

Neural stem and progenitor cell (NSPC) transplants provide neuroprotection in models of acute brain injury, but the underlying mechanisms are not fully understood. Here, we provide evidence that caspase-dependent apoptotic cell death of NSPCs is required for sending survival signals to the injured b...

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Autori principali: Han, Wei, Meißner, Eva-Maria, Neunteibl, Stefanie, Günther, Madeline, Kahnt, Jörg, Dolga, Amalia, Xie, Cuicui, Plesnila, Nikolaus, Zhu, Chaglian, Blomgren, Klas, Culmsee, Carsten
Natura: Articolo
Lingua:inglese
Pubblicazione: Philipps-Universität Marburg 2023
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