Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

Neural stem and progenitor cell (NSPC) transplants provide neuroprotection in models of acute brain injury, but the underlying mechanisms are not fully understood. Here, we provide evidence that caspase-dependent apoptotic cell death of NSPCs is required for sending survival signals to the injured b...

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Autoren: Han, Wei, Meißner, Eva-Maria, Neunteibl, Stefanie, Günther, Madeline, Kahnt, Jörg, Dolga, Amalia, Xie, Cuicui, Plesnila, Nikolaus, Zhu, Chaglian, Blomgren, Klas, Culmsee, Carsten
Formato: Artigo
Idioma:inglés
Publicado: Philipps-Universität Marburg 2023
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